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pAAV-hSyn-hM3D(Gq)-mCherry in Rat (AAV8)

Addgene #50474-AAV8

Data Submitted By
Todd Nentwig and L. Judson Chandler
Submission Date
December 19, 2020
Publication Date
December 19, 2020 (modified May 16, 2023)
Abstract
Not provided
Caption: Gq-DREADD expression in internal capsule-adjacent areas, eg, GP, EPN, Reticular Thalamus.

Any further use of this image requires permission from the lab who submitted the data.

Vector Used
pAAV-hSyn-hM3D(Gq)-mCherry
Addgene #50474-AAV8

Virus & Injection

Virus

Virus Name
pAAV-hSyn-hM3D(Gq)-mCherry
Serotype
AAV8
Source
Addgene
Catalog Number
50474-AAV8
Promoter
Synapsin
Cargo Type
Chemogenetics
Injection Titer / Dose
2.00E+12 GC/ml
Injection Volume
450nl
Injection Rate
1nl/sec
Injector Material
Not provided
Injection Site / Route
Reticular nucleus of the thalamus NeuroNames ID: 366
Additional Details
Forebrain: Basal Ganglia: Globus pallidus internal or entopeduncular nucleus
View in Addgene Catalog

Other Details

Species
Rat
Strain or Cell Line
Long-Evans
Age at Injection
~100 days old
Time After Injection
4 weeks
Detection Method
Immunohistochemistry
Functional Testing
Neurons expressing the excitatory DREADD exhibited robust induction of cFos following systemic injection of DREADD ligand, Deschloroclozapine