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pAAV-hSyn-DIO-hM3D(Gq)-mCherry in Mouse (AAV8)

Addgene #44361-AAV8

Data Submitted By
Victor Mathis and Paul Kenny
Submission Date
July 09, 2019
Publication Date
July 09, 2019 (modified May 16, 2023)
Abstract
Not Provided

Any further use of this image requires permission from the lab who submitted the data.

Vector Used
pAAV-hSyn-DIO-hM3D(Gq)-mCherry
Addgene #44361-AAV8

Virus & Injection

Virus

Virus Name
pAAV-hSyn-DIO-hM3D(Gq)-mCherry
Serotype
AAV8
Source
Addgene
Catalog Number
44361-AAV8
Promoter
Synapsin
Cargo Type
Chemogenetics
Injection Titer / Dose
4.80E+12 GC/ml
Injection Volume
250 nl
Injection Rate
125 nl/min
Injector Material
Not Provided
Injection Site / Route
Lateral habenula, NeuroNames ID: 295
Additional Details
All cells within the lateral habenula; Forebrain: Epithalamus; Lateral habenula, neurons
View in Addgene Catalog

Other Details

Species
Mouse
Strain or Cell Line
Vgat-cre
Source
Not provided
Age at Injection
8 weeks
Time After Injection
4 weeks
Detection Method
Direct fluorescence
Assay & Results
Not Provided
Functional Testing
CNO injected in mice 15 min prior test (3mg/kg). Behavioral response showed reproducibility with previous experiments (electrophysiological recordings in progress)
Tips & Comments
For local infusion I would use either an AAV5 or 8