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pAAV-hSyn-DIO-hM3D(Gq)-mCherry in Rat (AAV8)

Addgene #44361-AAV8

Data Submitted By
Tim O'neal and Susan Ferguson
Submission Date
June 28, 2019
Publication Date
June 28, 2019 (modified May 16, 2023)
Abstract
Not Provided
Caption: Confocal image, 20x magnification, 560nm excitation

Any further use of this image requires permission from the lab who submitted the data.

Vectors Used
pAAV-hSyn-DIO-hM3D(Gq)-mCherry
Addgene #44361-AAV8
CAV2-Cre

Virus & Injection

Virus 1

Virus Name
pAAV-hSyn-DIO-hM3D(Gq)-mCherry
Serotype
AAV8
Source
Addgene
Catalog Number
44361-AAV8
Promoter
Synapsin
Cargo Type
Chemogenetics
Injection Titer / Dose
2.50E+13 GC/mL
Injection Volume
500 nL
Injection Rate
100 nL/min
Injector Material
Not Provided
Injection Time
5 min
Injection Site / Route
Nucleus accumbens, NeuroNames ID: 277
Additional Details
Since injection was at the same site, both viruses were mixed 1:1 ratio and then a total of 1. 2 μl was injected to give 600 nl of each virus. We waited 5 min before removing the injection pipette from the injection site.
View in Addgene Catalog

Virus 2

Virus Name
CAV2-Cre
Serotype
N/A
Source
Unknown
Catalog Number
N/A
Promoter
Other
Other Promoter
Not Provided.
Cargo Type
Recombinase
Injection Titer / Dose
2.50E+09 GC/mL
Injection Volume
500 nL
Injection Rate
100 nL/min
Injector Material
Not Provided
Injection Time
5 min
Injection Site / Route
Substantia nigra, NeuroNames ID: 536

Other Details

Species
Rat
Strain or Cell Line
Outbred Sprague-Dawley
Source
Envigo
Stock Number
002
Age at Injection
8 weeks
Time After Injection
3 weeks
Detection Method
Immunohistochemistry
Assay & Results
Nucleus accumbens, direct pathway medium spiny neurons.