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pAAV.Syn.NES-jRGECO1a.WPRE.SV40 in Mouse (AAV1)

Addgene #100854-AAV1

Data Submitted By
Sindhuja Baskar and David Margolis
Submission Date
October 24, 2019
Publication Date
October 24, 2019 (modified May 16, 2023)
Abstract
Not Provided
Caption: Confocal image of mouse striatum and cortex showing jRGECO labeling.

Any further use of this image requires permission from the lab who submitted the data.

Vectors Used
pAAV.Syn.NES-jRGECO1a.WPRE.SV40
Addgene #100854-AAV1
pGP-AAV-syn-jGCaMP7f-WPRE
Addgene #104488-AAV1
pAAV-CaMKIIa-hChR2(H134R)-EYFP
Addgene #26969-AAV1

Virus & Injection

Virus 1

Virus Name
pAAV.Syn.NES-jRGECO1a.WPRE.SV40
Serotype
AAV1
Source
Addgene
Catalog Number
100854-AAV1
Promoter
Synapsin
Cargo Type
Biosensor
Injection Titer / Dose
2.40E+13 GC/mL
Injection Volume
~210-420 nL
Injection Rate
42-84 nL/min
Injector Material
Not Provided
Injection Site / Route
Primary motor cortex, NeuroNames ID: 1910
Additional Details
Injection site: whisker M1.
View in Addgene Catalog

Virus 2

Virus Name
pGP-AAV-syn-jGCaMP7f-WPRE
Serotype
AAV1
Source
Addgene
Catalog Number
104488-AAV1
Promoter
Synapsin
Cargo Type
Biosensor
Injection Titer / Dose
2.20E+13 GC/mL
Injection Volume
~210-420 nL
Injection Rate
42-84 nL/min
Injector Material
Not Provided
Injection Site / Route
Primary motor cortex, NeuroNames ID: 1910. Primary somatosensory cortex, NeuroNames ID: 1350. Posteromedian thalamic nucleus, NeuroNames ID: 1106.
Additional Details
Injection site: whisker M1. Injection site: whisker M1. Where: primary motor cortex (M1), primary somatosensory cortex (S1), striatum, posterior medial nucleus of the thalamus (POm).
View in Addgene Catalog

Virus 3

Virus Name
pAAV-CaMKIIa-hChR2(H134R)-EYFP
Serotype
AAV1
Source
Addgene
Catalog Number
26969-AAV1
Promoter
CaMKII
Cargo Type
Optogenetics
Injection Titer / Dose
1.00E+13 GC/mL
Injection Volume
~210 nL
Injection Rate
42 nL/min
Injector Material
Not Provided
Injection Site / Route
Posteromedian thalamic nucleus, NeuroNames ID: 1106
Additional Details
Injection site: whisker M1. Where: primary motor cortex (M1), primary somatosensory cortex (S1), striatum, posterior medial nucleus of the thalamus (POm).
View in Addgene Catalog

Other Details

Species
Mouse
Strain or Cell Line
C57Bl/6J, B6. Tg(Gpr26-cre)KO250
Source
Jackson Labs
Stock Number
000664
Age at Injection
49-78 days
Time After Injection
3 weeks
Detection Method
Fiber Photometry
Assay & Results
Not Provided