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pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA in Mouse (AAV5)

Addgene #20298-AAV5

Data Submitted By
Kengo Inada and Kazunari Miyamichi
Submission Date
July 31, 2019
Publication Date
July 31, 2019 (modified May 16, 2023)
Abstract
Not Provided
Caption: Right primary motor cortex expressing ChR2-YFP was shown. In situ hybridization was performed to enhance YFP signal (green). Blue, DAPI.

Any further use of this image requires permission from the lab who submitted the data.

Vectors Used
pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA
Addgene #20298-AAV5
pENN.AAV.hSyn.Cre.hGH
Addgene #105555-AAV9

Virus & Injection

Virus 1

Virus Name
pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA
Serotype
AAV5
Source
Addgene
Catalog Number
20298-AAV5
Promoter
EF1a
Cargo Type
Optogenetics
Injection Titer / Dose
7.70E+12 GC/ml
Injection Volume
200 nl
Injection Rate
50 nl/min
Injector Material
Not Provided
Injection Site / Route
Primary motor cortex, Neuronames ID: 1910
Additional Details
Primary motor cortex.
View in Addgene Catalog

Virus 2

Virus Name
pENN.AAV.hSyn.Cre.hGH
Serotype
AAV9
Source
Addgene
Catalog Number
105555-AAV9
Promoter
Synapsin
Cargo Type
Recombinase
Injection Titer / Dose
2.30E+13 GC/ml
Injection Volume
200 nl
Injection Rate
50 nl/min
Injector Material
Not Provided
Injection Site / Route
Primary motor cortex, Neuronames ID: 1910
Additional Details
Primary motor cortex.
View in Addgene Catalog

Other Details

Species
Mouse
Strain or Cell Line
C57/BL6J
Source
Not provided
Age at Injection
6 weeks old
Time After Injection
2 weeks
Detection Method
Immunohistochemistry, Direct fluorescence
Assay & Results
In situ hybridization was performed to enhance YFP signal.
Functional Testing
Yes