pAAV-hSyn-hM3D(Gq)-mCherry in Rat (AAV8)
Addgene #50474-AAV8

Gq-DREADD expression in internal capsule-adjacent areas, eg, GP, EPN, Reticular Thalamus.

Caption: Gq-DREADD expression in internal capsule-adjacent areas, eg, GP, EPN, Reticular Thalamus.

Virus & Injection

Primary Virus
Promoter
Syn
Injected Titer
2.00E+12 GC/ml
Injected Volume
450nl
Injection Rate
1nl/sec
Injection Site
Brain parenchyma
Brain Region
Forebrain: Basal Ganglia: Globus pallidus internal or entopeduncular nucleus
View in Addgene Catalog

Subject

Species / Strain
Rat Long-Evans
Age at Injection
~100 days old

Data Collection

Time After Injection
4 weeks
Detection Method
Immunohistochemistry
Genetic Tool Outcome
Neurons expressing the excitatory DREADD exhibited robust induction of cFos following systemic injection of DREADD ligand, Deschloroclozapine